Sources and Impact of IL-13 in Skin1
In AD skin, overexpression of IL-13 leads to disruption of the skin barrier, increased risk of skin infections, further amplified inflammation, itch—and, in the chronic phase, remodeling and dermal thickening.1-9
ILC, innate lymphoid cell; TEWL, transepidermal water loss; TSLP, thymic stromal lymphopoietin.